![]() These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the class to which this drug principally belongs. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. The color coatings contain polyvinyl alcohol, macrogol/ polyethylene glycol 3350, titanium dioxide, talc, iron oxide yellow (5/40 mg, 10/20 mg, 10/40 mg tablets), iron oxide red (10/20 mg and 10/40 mg tablets), and iron oxide black (10/20 mg tablets).Īzor is indicated for the treatment of hypertension, alone or with other antihypertensive agents, to lower blood pressure. Olmesartan medoxomil is practically insoluble in water and sparingly soluble in methanol.Įach tablet of Azor also contains the following inactive ingredients: silicified microcrystalline cellulose, pregelatinized starch, croscarmellose sodium, and magnesium stearate. Amlodipine besylate is slightly soluble in water and sparingly soluble in ethanol. The molecular weights of amlodipine besylate and olmesartan medoxomil are 567.1 and 558.59, respectively. The structural formula for olmesartan medoxomil is:Īzor contains amlodipine besylate, a white to off-white crystalline powder, and olmesartan medoxomil, a white to light yellowish-white powder or crystalline powder. The structural formula for amlodipine besylate is: The olmesartan medoxomil component of Azor is chemically described as 2,3dihydroxy-2-butenyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-imidazole-5-carboxylate, cyclic 2,3-carbonate. Olmesartan medoxomil, a prodrug, is hydrolyzed to olmesartan during absorption from the gastrointestinal tract. ![]() Its empirical formula is C 20H 25ClN 2O 5 ![]() The amlodipine besylate component of Azor is chemically described as 3-ethyl-5methyl (±)-2-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5pyridinedicarboxylate, monobenzenesulphonate. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus ( WARNINGS AND PRECAUTIONS).Īzor provided as a tablet for oral administration, is a combination of the calcium channel blocker (CCB) amlodipine besylate and the angiotensin II receptor blocker (ARB) olmesartan medoxomil.When pregnancy is detected, discontinue Azor as soon as possible ( WARNINGS AND PRECAUTIONS).
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